A new study published in the journal Anticancer Research titled, "Natural Products That Target Cancer Stem Cells," has made our job much easier of identifying this special category of cancer killers by reviewing the extant literature on the topic and listing the top 25 substances in this category. They are listed here below, along with some of their commonly recognizable dietary sources:
1. Epigallocatechin-3-gallate (EGCG) - Green Tea
2. 6-Gingerol - Ginger
3. β-Carotene - Carrot, Leafy Greens
4. Baicalein - Chinese Skullcap
6. Cyclopamine - Corn Lilly [we do not suggest consuming this plant; this simply illustrates natural components exist that kill cancer stem cells]
7. Delphinidin - Blueberry, raspberrry
8. Flavonoids (Genistein) - Soy, red clover, coffee
9. Gossypol - Cottonseed [we do not suggest consuming this plant; this simply illustrates natural components exist that kill cancer stem cells]
10. Guggulsterone - Commiphora (myrrh tree)
11. Isothiocyanates - Cruciferous vegetables
12. Linalool - Mint
13. Lycopene - Grapefruit, tomato
14. Parthenolide - Feverfew
15. Perylill alcohol - Mint, cherry, lavender
16. Piperine - Black pepper
17. Placycodon saponin - Playycodon grandifloruim
18. Psoralidin - Psoralea corylilyfolia
19. Quercetin - Capers, onion
20. Resveratrol - Grapes, plums, berries
21. Salinomycin - Streptomyces albus
22. Silibinin - Milk Thistle
23. Ursolic acid - Thyme, basil, oregano
24. Vitamin D3 - Fish, egg yolk, beef, cod liver oil
25. Withaferin A - Withania somnifera (ashwaganda)
Why are these substances so important?
The primary reason why conventional chemotherapy and radiotherapy have failed to produce any significant improvements in cancer survival rates is because cancer stem cells are resistant to these interventions. In fact, chemotherapy and especially radiation are both capable of increasing the number and virulence of these cells in a tumor, while at the same time having the well known side effect of further damaging the patient's immune system.
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Posted by: Pullamkottu Poulose Cherian <cherianpullamkottu@gmail.com>
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